1 Ağustos 2018 Çarşamba

Contributions to the IACAPAP 2018 Congress about Prenatal Thyroid Theory

Last week IACAPAP 2018 (23rd World Congress of the International Association for Child and Adolescent Psychiatry and Allied Professions) congress was held in Prague. Two contributions relating to Prenatal Thyroid Theory of Homosexuality found place in the programme all authored by Dr. Osman Sabuncuoglu. The first one was about a new group of youngsters explained by the prenatal thyroid theory. The audience followed the presentation with great interest and several questions were raised at the end. The second one was a poster presentation about the emerging roles for child and adolescent psychiatrist as a result of prenatal thyroid theory. Both of Sabuncuoglu's works can be accessed at the links below: https://www.researchgate.net/publication/326723698_A_second_group_of_youngsters_with_gender_nonconformitysame-sex_attraction_born_to_mothers_with_thyroid_dysfunction_in_pregnancy https://www.researchgate.net/publication/326723857_Prenatal_thyroid_theory_of_gender_nonconformitysame-sex_attraction_the_emerging_roles_for_child_and_adolescent_psychiatry

18 Şubat 2018 Pazar

A Contribution to Archives of Sexual Behavior by Dr. Osman Sabuncuoglu: Commentary on “Gay Male Only-Children: Evidence for Low Birth Weight and High Maternal Miscarriage Rates” from the Prenatal Thyroid Model Perspective

In the January 2018 Issue of Archives of Sexual Behavior, a commentary on the article of Skorska et al. (2017) has been published by Dr. Sabuncuoglu. Skorska et al. (2017) had viewed low birth in gay males and higher evidence of miscarriage in their mothers as an indication of a second type of maternal immune hypothesis. For Dr. Sabuncuoglu all the findings were an indication of prenatal thyroid theory, as higher risk for low birth weight and miscarriage in the mothers were all associated with maternal thyroid dysfunction. There is also a unique contribution in the paper. An in-depth explanation of fraternal birth order effect from prenatal thyroid theory perspective, as well as fetal microchmerism suggested in its etiopathogenesis. "...in my opinion, a comprehensive consideration of all thyroid issues is essential in the study of gender nonconformity and same-sex attraction." says Dr. Osman Sabuncuoglu The article is available at: https://link.springer.com/article/10.1007/s10508-017-1122-2

6 Şubat 2018 Salı

A Genome-Wide Study of Male Sexual Orientation Bolsters Prenatal Thyroid Theory

The authors (Alan Sanders et al., 2017) of a genome-wide association study have reported that male homosexual orientation is associated with two regions located on chromosomes 13 and 14. On chromosome 14, the thyroid stimulating hormone receptor (TSHR) gene was found to span the most significant region that confirms past findings relating familial atypical thyroid function and male homosexuality. In Graves's disease, TSHR codes for the major autoantigen in the autoimmune hyperthyroidism. The paper cites Sabuncuoglu's work as follows: "...…Furthermore, a recent retrospective chart review of 790 adolescents (8 to 17 years) previously admitted to a child psychiatry service found 15 mothers with a history of thyroid dysfunction during pregnancy, 16 adolescents with a history of same-sex attraction and/or gender nonconformity, and 12 overlapping mother-offspring pairs with both (p < 0.0001), suggestive of a possible relationship…" Headlined in several internet and mass media, the findings of the study was a great surprise for those who are still unaware of Prenatal Thyroid Theory. Even in an unlikely design to confirm the Prenatal Thyroid Theory, the positive findings are in no way surprising as Sabuncuoglu had noted in his 2015 paper that: "...…The genetic model is also under scrutiny. It is not surprising to find significant results for homosexuality in genetic studies as prevalent thyroid disorders (i.e., Hashimoto thyroiditis) have a very strong genetic background. In the search for possible factors for the persistence of homosexuality in human populations, thyroid disorders provide a reasonable explanation as they are prevalent and more common in women." We do not think that Graves's disease is the main path to contribute to male homosexuality. First of all, even Graves's disease is much more common in females. Yet we can eagerly claim that a genetic study on female homosexuals will reveal stronger positive results for Hashimoto's thyroiditis. As we note here :)